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Peer-reviewed, Pubmed-indexed publications

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Since 1994 Dr. Mattei has produced a total of >60 publications, of which numerous as Corresponding Author and First Author, listed below in descending chronological order.

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  • Raggi C, Spadaro F, Mattei F, Gambardella AR, Noto F, Andreone S, Signore M, Schiavoni G, Parolini I, Afferni C. Eosinophil-Airway Epithelial Cells crosstalk reveals the eosinophils-mediated DUOX1 up-regulation in a murine allergic inflammation setting. J Leukoc Biol. 2024 Oct 24:qiae232. doi: 10.1093/jleuko/qiae232. Epub ahead of print. PMID: 39447011.

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  • Gambardella AR, Antonucci C, Zanetti C, Noto F, Andreone S, Vacca D, Pellerito V, Sicignano C, Parrottino G, Tirelli V, Tinari A, Falchi M, De Ninno A, Businaro L, Loffredo S, Varricchi G, Tripodo C, Afferni C, Parolini I, Mattei F*, Schiavoni G*. IL-33 stimulates the anticancer activities of eosinophils through extracellular vesicle-driven reprogramming of tumor cells. (*) Corresponding Authors. J Exp Clin Cancer Res. 2024 Jul 27;43(1):209. doi: 10.1186/s13046-024-03129-1. PMID: 39061080; PMCID: PMC11282757.

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  • ​Cancila V, Morello G, Bertolazzi G, Chan AS, Bastianello G, Paysan D, Jaynes PW, Schiavoni G, Mattei F, Piconese S, Revuelta MV, Noto F, De Ninno A, Cammarata I, Pagni F, Venkatachalapathy S, Sangaletti S, Di Napoli A, Vacca D, Lonardi S, Lorenzi L, Ferreri AJM, Belmonte B, Varano G, Colombo MP, Bicciato S, Inghirami G, Cerchietti L, Ponzoni M, Zappasodi R, Facchetti F, Foiani M, Casola S, Jeyasekharan AD, Tripodo C. Germinal Center Dark Zone harbors ATR-dependent determinants of T-cell exclusion that are also identified in aggressive lymphoma. Res Sq [Preprint]. 2024 Mar 18:rs.3.rs-4093618. doi: 10.21203/rs.3.rs-4093618/v1. PMID: 38562878; PMCID: PMC10984086.

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  • Antonucci C., Gambardella A.R., Tirelli V., Mattei F.*, Schiavoni G.* (2024) Complementary methods for the study of interactions between eosinophils and cancer cells. (*) Corresponding Authors. bioRxiv. doi: https://doi.org/10.1101/2024.04.25.590232

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  • Gambardella A.R., Tirelli V., Andreone S., Mancini J., Mattei F.*, Schiavoni G.* (2024) Combined in vitro differentiation and cell sorting-based isolation of highly pure mouse bone marrow-derived basophils. (*) Corresponding Authors. bioRxiv. doi: https://doi.org/10.1101/2024.04.25.591228

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  • Noto F., De Ninno A., Falchi M., Businaro L., Schiavoni G.*, Mattei F.* (2024) Organ-on-Chip immunostaining method for three-dimensional identification and study of immune cells responding to drug-treated tumor cells. (*) Corresponding Authors. BioRXiv. DOI: https://doi.org/10.1101/2024.04.24.590383

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  • Mattei F., George J.T., and Jolly M. (2023) Editorial: Organoids, Organs-on-Chip, nanoparticles and In Silico Approaches to Dissect the Tumor-Immune Dynamics and to Unveil the Drug Resistance Mechanisms to Therapy in the Tumor Microenvironment. Front. Immunol. 14:1253551. doi: 10.3389/fimmu.2023.1253551 (Editorial).

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  • Dong P., Mattei F. and Lindsay M.A. (2023) Editorial: Non-coding RNA in improving the efficacy of cancer immunotherapy. Front. Immunol. 14:1210235. doi: 10.3389/fimmu.2023.1210235 (Editorial).

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  • Mattei F.*, Jolly M. K. Interdisciplinary research in cancer and immunity employing biophysical approaches. iScience. 2023 26(5):106507. DOI: 10.1016/j.isci.2023.106507. (*) Corresponding Author (Editorial).

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  • Poto R, Gambardella AR, Marone G, Schroeder JT, Mattei F, Schiavoni G, Varricchi G. Basophils from allergy to cancer. Front Immunol. 2022 Dec 12;13:1056838. doi: 10.3389/fimmu.2022.1056838. PMID: 36578500; PMCID: PMC9791102.

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  • Mattei F, Della Rocca G, Schiavoni G, Paoletti E, Afferni C. Traffic-related NO2 affects expression of Cupressus sempervirens L. pollen allergens. Ann Agric Environ Med. 2022 Jun 24;29(2):232-237. doi: 10.26444/aaem/146607. Epub 2022 Apr 6. PMID: 35767756

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  • Mattei F., Andreone S., Spadaro F., Noto F., Tinari A., Falchi M., Piconese S., Afferni C., Schiavoni G. Trogocytosis in innate immunity to cancer is an intimate relationship with unexpected outcomes. iScience (2022). DOI:10.1016/j.isci.2022.105110

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  • Musella M, Guarracino A, Manduca N, Galassi C, Ruggiero E, Potenza A, Maccafeo E, Manic G, Mattiello L, Soliman Abdel Rehim S, Signore M, Pietrosanto M, Helmer-Citterich M, Pallocca M, Fanciulli M, Bruno T, De Nicola F, Corleone G, Di Benedetto A, Ercolani C, Pescarmona E, Pizzuti L, Guidi F, Sperati F, Vitale S, Macchia D, Spada M, Schiavoni G, Mattei F, De Ninno A, Businaro L, Lucarini V, Bracci L, Aricò E, Ziccheddu G, Facchiano F, Rossi S, Sanchez M, Boe A, Biffoni M, De Maria R, Vitale I, Sistigu A. Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B. Nature Immunology (2022). DOI:10.1038/s41590-022-01290-3. PMID: 36002648.

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  • Gambardella A.R.; Poto R.; Tirelli V.; Schroeder J.T.; Marone G.; Mattei F.; Varricchi G.; Schiavoni G. Differential Effects of Alarmins on Human and Mouse Basophils (2022) Frontiers in Immunology, DOI:10.3389/fimmu.2022.894163.

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  • Mattei, F.*; Alfaro, C.; Keisari, Y. Cancer Immunology: From Molecular Mechanisms to Therapeutic Opportunities (2022) Cells, 11, 459. DOI:10.3390/cells11030459. (*) Corresponding Author (Editorial).

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  • Mattei, F.; Della Rocca, G.; Schiavoni, G.; Paoletti, E.; Afferni C. Traffic-related NO2 affects expression of Cupressus sempervirens L. pollen allergens (2022) Annals of Agricultural and Environmental Medicine. https://doi.org/10.26444/aaem/146607.

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  • Boussadia, Z.; Gambardella, A.R.; Mattei, F.*; Parolini, I.* Acidic and Hypoxic Microenvironment in Melanoma: Impact of Tumour Exosomes on Disease Progression. Cells 2021, 10, 3311. https://doi.org/10.3390/cells10123311. (*) Corresponding Authors.

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  • Ciccolella M., Andreone S., Mancini J., Sestili P., Negri D., Pacca A.M., D’Urso M.T., Macchia D., Canese R., Pang K., Sai Ying Ko T., Decadt Y., Schiavoni G., Mattei, F., Belardelli F., Aricò E., Bracci L. Anticancer effects of sublingual type I IFN in combination with chemotherapy in implantable and spontaneous tumor models (2021) Cells, 10(4):845. DOI: 10.3390/cells10040845.

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  • Mattei F., Andreone S., Mencattini A., De Ninno A., Businaro L., Martinelli E., Schiavoni G. Oncoimmunology Meets Organs-On-Chip (2021) Frontiers in Molecular Biosciences DOI: 10.3389/fmolb.2021.627454

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  • Comes, M.C., Filippi, J., Mencattini, A., Corsi, F., Casti, P., De Ninno, A., Di Giuseppe, D., D’Orazio, M., Ghibelli, L., Mattei, F., Schiavoni, G., Businaro, L., Di Natale, C., Martinelli, E. Accelerating the experimental responses on cell behaviors: a long-term prediction of cell trajectories using Social Generative Adversarial Network (2020) Scientific Reports, 10 (1), art. no. 15635, DOI: 10.1038/s41598-020-72605-3

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  • De Ninno A, Bertani FR, Gerardino A, Schiavoni G, Musella M, Galassi C, Mattei F, Sistigu A, Businaro L. Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments. J Vis Exp. 2021 Apr 30;(170). doi: 10.3791/61895. PMID: 33999026.

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  • Andreone, S., Gambardella, A.R., Mancini, J., Loffredo, S., Marcella, S., La Sorsa, V., Varricchi, G., Schiavoni, G., Mattei, F. Anti-Tumorigenic Activities of IL-33: A Mechanistic Insight (2020) Frontiers in Immunology, 11, art. no. 571593.

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  • Marone, G., Schroeder, J.T., Mattei, F., Loffredo, S., Gambardella, A.R., Poto, R., de Paulis, A., Schiavoni, G., Varricchi, G. Is There a Role for Basophils in Cancer? (2020) Frontiers in Immunology, 11, art. no. 2103, DOI: 10.3389/fimmu.2020.02103

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  • Rossi, A., Lucarini, V., Macchia, I., Sestili, P., Buccione, C., Donati, S., Ciccolella, M., Sistigu, A., D'Urso, M.T., Pacca, A.M., Cardarelli, E., Mattei, F., Proietti, E., Schiavoni, G., Bracci, L. Tumor-Intrinsic or Drug-Induced Immunogenicity Dictates the Therapeutic Success of the PD1/PDL Axis Blockade (2020) Cells, 9 (4), DOI: 10.3390/cells9040940

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  • Mattei F., Andreone S., Schiavoni G. A Clonogenic Assay to Quantify Melanoma Micrometastases in Pulmonary Tissue (2021) Methods In Molecular Biology 2265:385-406. DOI:10.1007/978-1-0716-1205-7_28.

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  • Marone, G., Gambardella, A.R., Mattei, F., Mancini, J., Schiavoni, G., Varricchi, G. Basophils in Tumor Microenvironment and Surroundings (2020) Advances in Experimental Medicine and Biology, 1224, pp. 21-34.

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  • Mattei, F., Andreone, S., Marone, G., Gambardella, A.R., Loffredo, S., Varricchi, G., Schiavoni, G. Eosinophils in the Tumor Microenvironment (2020) Advances in Experimental Medicine and Biology, 1273, pp. 1-28.

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  • Mencattini, A., De Ninno, A., Mancini, J., Businaro, L., Martinelli, E., Schiavoni, G., Mattei, F. High-throughput analysis of cell-cell crosstalk in ad hoc designed microfluidic chips for oncoimmunology applications (2020) Methods in Enzymology, 632, pp. 479-502. DOI: 10.1016/bs.mie.2019.06.012

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  • Comes, M.C., Filippi, J., Mencattini, A., Casti, P., Cerrato, G., Sauvat, A., Vacchelli, E., De Ninno, A., Di Giuseppe, D., D’Orazio, M., Mattei, F., Schiavoni, G., Businaro, L., Di Natale, C., Kroemer, G., Martinelli, E. Multi-scale generative adversarial network for improved evaluation of cell–cell interactions observed in organ-on-chip experiments (2020) Neural Computing and Applications, DOI: 10.1007/s00521-020-05226-6

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  • Andreone, S., Spadaro, F., Buccione, C., Mancini, J., Tinari, A., Sestili, P., Gambardella, A.R., Lucarini, V., Ziccheddu, G., Parolini, I., Zanetti, C., D'urso, M.T., De Ninno, A., Businaro, L., Afferni, C., Mattei, F., Schiavoni, G. IL-33 promotes CD11b/CD18-mediated adhesion of eosinophils to cancer cells and synapse-polarized degranulation leading to tumor cell killing (2019) Cancers, 11 (11), art. no. 1664.

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  • Mencattini, A., Mattei, F., Schiavoni, G., Gerardino, A., Businaro, L., Di Natale, C., Martinelli, E. From petri dishes to organ on chip platform: The increasing importance of machine learning and image analysis (2019) Frontiers in Pharmacology, 10, art. no. 100.

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  • Afferni, C., Buccione, C., Andreone, S., Galdiero, M.R., Varricchi, G., Marone, G., Mattei, F., Schiavoni, G. The pleiotropic immunomodulatory functions of IL-33 and its implications in tumor immunity (2018) Frontiers in Immunology, 9 (NOV), art. no. 2601.

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  • Boussadia, Z., Lamberti, J., Mattei, F., Pizzi, E., Puglisi, R., Zanetti, C., Pasquini, L., Fratini, F., Fantozzi, L., Felicetti, F., Fecchi, K., Raggi, C., Sanchez, M., D'Atri, S., Carè, A., Sargiacomo, M., Parolini, I. Acidic microenvironment plays a key role in human melanoma progression through a sustained exosome mediated transfer of clinically relevant metastatic molecules (2018) Journal of Experimental and Clinical Cancer Research, 37 (1), art. no. 245.

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  • Varricchi, G., Galdiero, M.R., Loffredo, S., Lucarini, V., Marone, G., Mattei, F., Marone, G., Schiavoni, G. Eosinophils: The unsung heroes in cancer? (2018) OncoImmunology, 7 (2), art. no. e1393134.

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  • Biselli, E., Agliari, E., Barra, A., Bertani, F.R., Gerardino, A., De Ninno, A., Mencattini, A., Di Giuseppe, D., Mattei, F., Schiavoni, G., Lucarini, V., Vacchelli, E., Kroemer, G., Di Natale, C., Martinelli, E., Businaro, L. Organs on chip approach: A tool to evaluate cancer-immune cells interactions (2017) Scientific Reports, 7 (1), art. no. 12737.

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  • Lucarini, V., Ziccheddu, G., Macchia, I., La Sorsa, V., Peschiaroli, F., Buccione, C., Sistigu, A., Sanchez, M., Andreone, S., D'Urso, M.T., Spada, M., Macchia, D., Afferni, C., Mattei, F., Schiavoni, G. IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils (2017) OncoImmunology, 6 (6), art. no. e1317420.

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  • Lucarini, V., Buccione, C., Ziccheddu, G., Peschiaroli, F., Sestili, P., Puglisi, R., Mattia, G., Zanetti, C., Parolini, I., Bracci, L., Macchia, I., Rossi, A., D'Urso, M.T., Macchia, D., Spada, M., De Ninno, A., Gerardino, A., Mozetic, P., Trombetta, M., Rainer, A., Businaro, L., Schiavoni, G., Mattei, F. Combining Type I Interferons and 5-Aza-2′-Deoxycitidine to Improve Anti-Tumor Response against Melanoma (2017) Journal of Investigative Dermatology, 137 (1), pp. 159-169.

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  • De Santis, E., Masi, S., Cordone, I., Pisani, F., Zuppi, C., Mattei, F., Conti, L., Cigliana, G. Follow-up of IgD-κ multiple myeloma by monitoring free light chains and total heavy chain IgD: A case report (2016) Oncology Letters, 12 (3), pp. 1884-1888.

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  • Vacchelli, E., Ma, Y., Baracco, E.E., Sistigu, A., Enot, D.P., Pietrocola, F., Yang, H., Adjemian, S., Chaba, K., Semeraro, M., Signore, M., Ninno, A.D., Lucarini, V., Peschiaroli, F., Businaro, L., Gerardino, A., Manic, G., Ulas, T., Günther, P., Schultze, J.L., Kepp, O., Stoll, G., Lefebvre, C., Mulot, C., Castoldi, F., Rusakiewicz, S., Ladoire, S., Apetoh, L., Pedro, J.M.B.-S., Lucattelli, M., Delarasse, C., Boige, V., Ducreux, M., Delaloge, S., Borg, C., André, F., Schiavoni, G., Vitale, I., Laurent-Puig, P., Mattei, F., Zitvogel, L., Kroemer, G. Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1 (2015) Science, 350 (6263), pp. 972-978.

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  • Agliari, E., Biselli, E., De Ninno, A., Schiavoni, G., Gabriele, L., Gerardino, A., Mattei, F., Barra, A., Businaro, L. Cancer-driven dynamics of immune cells in a microfluidic environment (2014) Scientific Reports, 4, art. no. 6639,

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  • Mattei, F., Schiavoni, G., De Ninno, A., Lucarini, V., Sestili, P., Sistigu, A., Fragale, A., Sanchez, M., Spada, M., Gerardino, A., Belardelli, F., Businaro, L., Gabriele, L. A multidisciplinary study using in vivo tumor models and microfluidic cell-on-chip approach to explore the cross-talk between cancer and immune cells (2014) Journal of Immunotoxicology, 11 (4), pp. 337-346.

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  • Galluzzi, L., Vacchelli, E., Bravo-San Pedro, J.-M., Buqué, A., Senovilla, L., Baracco, E.E., Bloy, N., Castoldi, F., Abastado, J.-P., Agostinis, P., Apte, R.N., Aranda, F., Ayyoub, M., Beckhove, P., Blay, J.-Y., Bracci, L., Caignard, A., Castelli, C., Cavallo, F., Celis, E., Cerundolo, V., Clayton, A., Colombo, M.P., Coussens, L., Dhodapkar, M.V., Eggermont, A.M., Fearon, D.T., Fridman, W.H., Fucíková, J., Gabrilovich, D.I., Galon, J., Garg, A., Ghiringhelli, F., Giaccone, G., Gilboa, E., Gnjatic, S., Hoos, A., Hosmalin, A., Jäger, D., Kalinski, P., Kärre, K., Kepp, O., Kiessling, R., Kirkwood, J.M., Klein, E., Knuth, A., Lewis, C.E., Liblau, R., Lotze, M.T., Lugli, E., Mach, J.-P., Mattei, F., Mavilio, D., Melero, I., Melief, C.J., Mittendorf, E.A., Moretta, L., Odunsi, A., Okada, H., Palucka, A.K., Peter, M.E., Pienta, K.J., Porgador, A., Prendergast, G.C., Rabinovich, G.A., Restifo, N.P., Rizvi, N., Sautès-Fridman, C., Schreiber, H., Seliger, B., Shiku, H., Silva-Santos, B., Smyth, M.J., Speiser, D.E., Spisek, R., Srivastava, P.K., Talmadge, J.E., Tartour, E., Van Der Burg, S.H., Van Den Eynde, B.J., Vile, R., Wagner, H., Weber, J.S., Whiteside, T.L., Wolchok, J.D., Zitvogel, L., Zou, W., Kroemer, G. Classification of current anticancer immunotherapies (2014) Oncotarget, 5 (24), pp. 12472-12508.

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  • Schiavoni, G., Gabriele, L., Mattei, F. The tumor microenvironment: A pitch for multiple players (2013) Frontiers in Oncology, 3 APR, art. no. 00090.

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  • Schiavoni, G., Mattei, F., Gabriele, L. Type I interferons as stimulators of DC-mediated cross-priming: Impact on anti-tumor response (2013) Frontiers in Immunology, 4 (DEC), art. no. 483.

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  • Schiavoni, G., Gabriele, L., Mattei, F. The dual role of IRF8 in cancer immunosurveillance (2013) OncoImmunology, 2 (8), art. no. e25476.

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  • Palma, C., Schiavoni, G., Abalsamo, L., Mattei, F., Piccaro, G., Sanchez, M., Fernandez, C., Singh, M., Gabriele, L. Mycobacterium tuberculosis PstS1 amplifies IFN-γ and induces IL-17/IL-22 responses by unrelated memory CD4+ T cells via dendritic cell activation (2013) European Journal of Immunology, 43 (9), pp. 2386-2397.

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  • Rocca, S., Schiavoni, G., Sali, M., Anfossi, A.G., Abalsamo, L., Palucci, I., Mattei, F., Sanchez, M., Giagu, A., Antuofermo, E., Fadda, G., Belardelli, F., Delogu, G., Gabriele, L. Interferon Regulatory Factor 8-Deficiency Determines Massive Neutrophil Recruitment but T Cell Defect in Fast Growing Granulomas during Tuberculosis (2013) PLoS ONE, 8 (5), art. no. e62751.

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  • Businaro, L., De Ninno, A., Schiavoni, G., Lucarini, V., Ciasca, G., Gerardino, A., Belardelli, F., Gabriele, L., Mattei, F. Cross talk between cancer and immune cells: Exploring complex dynamics in a microfluidic environment (2013) Lab on a Chip, 13 (2), pp. 229-239.

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  • Gabriele, L., Schiavoni, G., Mattei F., Sanchez, M., Sestili, P., Butteroni, C., Businaro, R., Mirchandani, A., Niedbala, W., Liew, F.Y., Afferni, C. Novel allergic asthma model demonstrates ST2-dependent dendritic cell targeting by cypress pollen (2013) Journal of Allergy and Clinical Immunology, 132 (3), pp. 686-695.e7.

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  • Mattei, F., Schiavoni, G. TIM-3 as a molecular switch for tumor escape from innate immunity (2012) Frontiers in Immunology, 3 (JAN), art. no. Article 418.

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  • Mattei, F., Schiavoni, G., Sestili, P., Spadaro, F., Fragale, A., Sistigu, A., Lucarini, V., Spada, M., Sanchez, M., Scala, S., Battistini, A., Belardelli, F., Gabriele, L. IRF-8 controls melanoma progression by regulating the cross talk between cancer and immune cells within the tumor microenvironment (2012) Neoplasia (United States), 14 (12), pp. 1223-1235.

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  • Lorenzi, S., Mattei, F., Sistigu, A., Bracci, L., Spadaro, F., Sanchez, M., Spada, M., Belardelli, F., Gabriele, L., Schiavoni, G. Type I IFNs control antigen retention and survival of CD8α + dendritic cells after uptake of tumor apoptotic cells leading to cross-priming (2011) Journal of Immunology, 186 (9), pp. 5142-5150.

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  • Schiavoni, G., Sistigu, A., Valentini, M., Mattei, F., Sestili, P., Spadaro, F., Sanchez, M., Lorenzi, S., D'Urso, M.T., Belardelli, F., Gabriele, L., Proietti, E., Bracci, L. Cyclophosphamide synergizes with type I interferons through systemic dendritic cell reactivation and induction of immunogenic tumor apoptosis (2011) Cancer Research, 71 (3), pp. 768-778.

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  • Mattei, F., Schiavoni, G., Tough, D.F. Regulation of immune cell homeostasis by type I interferons (2010) Cytokine and Growth Factor Reviews, 21 (4), pp. 227-236.

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  • Mattei, F., Bracci, L., Tough, D.F., Belardelli, F., Schiavoni, G. Type I IFN regulate DC turnover in vivo (2009) European Journal of Immunology, 39 (7), pp. 1807-1818.

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  • Mattei, F., Schiavoni, G., Borghi, P., Venditti, M., Canini, I., Sestili, P., Pietraforte, I., Morse III, H.C., Ramoni, C., Belardelli, F., Gabriele, L. ICSBP/IRF-8 differentially regulates antigen uptake during dendritic-cell development and affects antigen presentation to CD4+ T cells (2006) Blood, 108 (2), pp. 609-617.

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  • Rothfuchs, A.G., Trumstedt, C., Mattei, F., Schiavoni, G., Hidmark, Å., Wigzell, H., Rottenberg, M.E. STAT1 regulates IFN-αβ- and IFN-γ-dependent control of infection with Chlamydia pneumoniae by nonhemopoietic cells (2006) Journal of Immunology, 176 (11), pp. 6982-6990.

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  • Schiavoni, G., Mattei, F., Borghi, P., Sestili, P., Venditti, M., Morse III, H.C., Belardelli, F., Gabriele, L. ICSBP is critically involved in the normal development and trafficking of Langerhans cells and dermal dendritic cells (2004) Blood, 103 (6), pp. 2221-2228.

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  • Schiavoni, G., Mattei, F., Sestili, P., Borghi, P., Venditti, M., Morse III, H.C., Belardelli, F., Gabriele, L. ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8α+ dendritic cells (2002) Journal of Experimental Medicine, 196 (11), pp. 1415-1425.

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  • Montoya M, Schiavoni G, Mattei, F, Gresser I, Belardelli F, Borrow P, Tough DF. Type I interferons produced by dendritic cells promote their phenotypic and functional activation (2002) Blood, 99(9), pp. 3263-3271.

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  • Mattei, F., Schiavoni, G., Belardelli, F., Tough, D.F. IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation (2001) Journal of Immunology, 167 (3), pp. 1179-1187.

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  • Schiavoni, G., Mattei, F., Di Pucchio, T., Santini, S.M., Bracci, L., Belardelli, F., Proietti, E. Cyclophosphamide induces type I interferon and augments the number of CD44(hi) T lymphocytes in mice: Implications for strategies of chemoimmunotherapy of cancer (2000) Blood, 95 (6), pp. 2024-2030.

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  • Alvino, S., Mosiello, A., Avilii, G., Mattei, F., Cianciulli, A.M., Gandolfo, G.M., Greco, C. Diagnostic and prognostic role in immunophenotypic markers for plasma cell dyscrasias (1997) Cell Proliferation, 30 (10-12), p. 450.

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  • Greco, C., Mattei, F., Alvino, S., Avilii, G., La Penta, R., Mosiello, A., Cianciulli, A.M., Casale, V., Gandolfo, G.M. Apoptosis, oncogenes and colon cancer progression (1997) Cell Proliferation, 30 (10-12), p. 452.

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  • Greco, C., Alvino, S., Mosiello, A., Avilii, G., Mattei, F., Francavilla, V., Valente, F., Del Monte, G., Cianciulli, A.M., Gandolfo, G.M. Monoclonal gammopathies with a high MC elicit altered phenotypic and genotypic features. (1997) European journal of histochemistry : EJH, 41 Suppl 2, pp. 19-20.

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  • Greco, C., Alvino, S., Marcucci, M., Mosiello, A., Mattei, F., Valente, F., Francavilla, V., Arista, C., Cianciulli, A.M., Gandolfo, G.M. Possible use of lymphoid CD subsets as prognostic markers for plasma cell dyscrasias. (1997) European journal of histochemistry : EJH, 41 Suppl 2, pp. 21-22.

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  • Gradilone, A., Greco, C., Gazzaniga, P., Vercillo, R., Napolitano, M., Gandini, O., Mattei, F., Frati, L., Agliano, A.M. Bax gene expression in melanoma metastases [4] (1996) Journal of Investigative Dermatology, 106 (2), p. 382.

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  • Greco, C., Ameglio, F., Alvino, S., Cianciulli, A.M., Giovannelli, M., Mattei, F., Vitelli, G., Venturo, I., Lopez, M., Gandolfo, G.M. Selection of patients with monoclonal grammopathy of undetermined significance is mandatory for a reliable use of interleukin-6 and other nonspecific multiple myeloma serum markers (1994) Acta Haematologica, 92 (1), pp. 1-7.

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  • Greco, C., Gandolfo, G.M., Mattei, F., Gradilone, A., Alvino, S., Pastore, L.I., Casale, V., Casole, P., Grassi, A., Cianciulli, A.M., Agliano, A.M. Detection of c-myb genetic alterations and mutant p53 serum protein in patients with benign and malignant colon lesions (1994) Anticancer Research, 14(3b):1433-1440.

 

Peer-reviewed Book Chapters

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  • Mattei F. et al. (2020) Eosinophils in the Tumor Microenvironment. In: Birbrair A. (eds) Tumor Microenvironment. Advances in Experimental Medicine and Biology, vol 1273. Springer, Cham. https://doi.org/10.1007/978-3-030-49270-0_1

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  • Mattei F.*, Andreone S., Schiavoni G.* A Clonogenic Assay to Quantify Melanoma Micrometastases in Pulmonary Tissue. Methods Mol Biol, 2020. In press. *Corresponding Authors.

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  • Mencattini A, De Ninno A, Mancini J, , Businaro L, Martinelli E, Schiavoni G*, Mattei F* 'High-throughput analysis of cell-cell crosstalk in ad hoc designed microfluididc chips for oncoimmunology applications', Methods in Enzymology, 2019, 632:479-502. *Corresponding Authors. DOI: 10.1016/bs.mie.2019.06.012.

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  • Marone G, Gambardella AR, Mattei F, Mancini J, Schiavoni G, Varricchi G. Basophils in Tumor Microenvironment and Surroundings. Adv Exp Med Biol. 2020;1224:21–34. doi:10.1007/978-3-030-35723-8_2

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Congress abstracts:

 

  • Sara Andreone, Francesca Spadaro, Iole Macchia, Mario Falchi, Antonella Tinari, Silvia Piconese, Claudia Afferni, Fabrizio Mattei, Giovanna Schiavoni. "Eosinophils acquire immune checkpoint molecules through trogocytosis: implications in cancer immunity" XIII SIICA International Congress, May 23-26, 2022, Naples, Italy.

 

  • Adriana Rosa Gambardella, Sara Andreone, JacopoMancini, Chiara Sicignano, Adele De Ninno, Giovanna Ziccheddu, Cristiana Zanetti, Isabella Parolini, LucaBusinaro, Claudia Afferni, Gianni Marone, Fabrizio Mattei, Giovanna Schiavoni. "Eosinophils and Interleukin-33 -mediated anticancer activities: role of exosomes in shaping tumor phenotype" 4th Meeting of Alliance Against Cancer - New Technologies and Strategies to Fight Cancer, November 20-22 2019, Rome, Italy.

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  • Francesco Noto, Sara Andreone, Adriana RosaGambardella, Chiara Sicignano, Jacopo Mancini, Carla Buccione, Adele De Ninno, Maria Teresa D’Urso, Daniele Macchia, Massimo Spada, Luca Businaro, Claudia Afferni, Fabrizio Mattei, Giovanna Schiavoni. "Epigenetic targeting of melanoma with Decitabine enhances the IL-33/ST2 pathway and improves the antitumoral activity of IL-33 in vitro and in vivo" 4th Meeting of Alliance Against Cancer - New Technologies and Strategies to Fight Cancer, November 20-22 2019, Rome, Italy.

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  • Sara Andreone, Francesca Spadaro, Jacopo Mancini, Adriana Rosa Gambradcella, Antonella Tinari, Paola Sestili, Carla Buccione, Valeria Lucarini, Giovanna Ziccheddu, Isabella Parolini, Cristiana Zanetti, Maria Teresa D'Urso, Claudia Afferni, Fabrizio Mattei, Giovanna Schiavoni. "IL-33 promotes CD11b/CD18-mediated adhesion of eosinophils to cancer cells and synapse-polarized degranulation leading to tumor cell killing" 4th Meeting of Alliance Against Cancer - New Technologies and Strategies to Fight Cancer, November 20-22 2019, Rome, Italy.

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  • Fabrizio Mattei, Carla Buccione, Sara Andreone, Francesca Spadaro, Adele De Ninno, Jacopo Mancini, Cristiana Zanetti, Isabella Parolini, Francesca Iosi, Antonella Tinari, Valeria Lucarini, Annamaria Gerardino, Giovanna Ziccheddu, Luca Businaro, Claudia Afferni, Giovanna Schiavoni. "IL-33 activates antitumoral toxicity in eosinophils through stimulation of contact-dependent degranulation." 4th CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference - TRANSLATING SCIENCE INTO SURVIVAL, September 30 - October 3, 2018, New York, USA.

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  • Mattei F. "Microfluidic technology as a new tool to investigate cancer and immune cells crosstalk for immunotherapy" 5th Cancer Immunotherapy and Immunomonitoring Conference, April 24-28, 2017, Prague, Czech Republic (Invited Speaker).

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  • Lucarini V, Ziccheddu G, Macchia I, La Sorsa V, Peschiaroli F, Buccione C, Sistigu A,Afferni C, Mattei F, Schiavoni G. "IL-33 inhibits melanoma growth and pulmonary metastasis in mice through recruitment and activation of eosinophils" European Cancer Organization-EACR-AACR-SIC Special Conference, Florence, Italy, June 24-27, 2017.

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  • Lucarini V, La Sorsa V, Macchia I, Peschiaroli F, Ziccheddu G, Buccione C, Sistigu A, Mattei F, Afferni C, Schiavoni G. “IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma bearing mice through active recruitment of eosinophils in the lung” NIBIT Congress, Siena, Italy, October 8-10, 2015.

 

  • Lucarini V, Buccione C, Ziccheddu G, Sestili P, Peschiaroli F, De Ninno A, Sistigu A, Macchia D, Spada M, Gabriele L, Gerardino A, Businaro L, Belardelli F, Schiavoni G, Mattei F.  “Combining Type I IFN and 5-Aza-2’-Deoxycitidine to improve anti-tumor response against melanoma.” NIBIT Congress, Siena, Italy, October 8-10, 2015.

 

  • Mattei F. Combining Type I IFN and 5'-Aza-2'-deoxycitidine to improve anti-tumor response against melanoma. 4th Cancer Immunotherapy and Immunomonitoring Conference, April 27-30. 2015, Ljubljana (Slovenia) (Invited Speaker).

 

  • Mattei F. “Employment of DNA demethylating agents to improve the anti-tumoral response of Type I Interferons in melanoma” Workshop “New technologies in biomedicine” 15 Dicembre 2015, Università Campus Biomedico Roma, Rome, Italy. (Invited Speaker).

 

  • Mattei F., Buoncervello M., Lucarini V., Romagnoli G., Toschi E., Fragale A., Giuliani C., Musella M., Spada M., Belardelli F., Schiavoni G., Gabriele L. “Type I IFN and 5-Aza-2’-Deoxycitidine synergize for the inhibition of solid cancer progression”. IFN Fundamentals 2014 – From Molecular Mechanisms to Human Diseases – Rome, Italy, February 20, 2014.

 

  • Mattei F., Buoncervello M., Romagnoli G.,Toschi E., Lucarini V., Fragale A., Giuliani C., Musella M., Spada M., Canini I., Belardelli F., Schiavoni G., Gabriele L. “Combined synergy between Type I IFN and 5-Aza-2’-Deoxycitidine in the inhibition of solid cancer progression”. First ISS-ARTOI Conference of Integrative Oncology – Rome, Italy, 6-7 November 2013.

 

  • Mattei F. Exploring the cross-talk between immune cells and cancer by a Cell-on-Chip approach. 2nd Cancer Immunotherapy and Immunomonitoring Conference, April 22-25. 2013, Krakow (Poland) (Invited Speaker).

 

  • Gabriele L., Schiavoni G., Mattei F., Sanchez M., Sestili P., Businaro R. & Afferni C. (2012) The treatment with native Cupressus arizonica major allergen (nCup a1), induces Th2-related chemokines and epithelial-derived pro-allergenic factors in lung of Balb/c mice. In: Allergy, Vol. 67, pp. 393-393.

 

  • Mattei F., Schiavoni G., Fragale A., Sistigu A., Spada M., Battistini A., Sestili P., Sanchez M., Gabriele L. IRF-8 controls melanoma progression by regulating cancer and immune cell cross-talk within the tumor microenvironment. 2nd Cancer Immunotherapy and Immunomonitoring Conference, May 2-5. 2011, Budapest (Hungary) (Oral Communication).

 

  • Lorenzi S., Mattei F., Spadaro F., Sanchez M., Sistigu A., Bracci L., Belardelli F., Gabriele L., Schiavoni G. “Type I IFN promote antigen retention by CD8+ DC after uptake of tumor apoptotic cells thus stimulating cross presentation”. DC2010: Forum on Vaccine Science – 11th International Symposium on Dendritic Cells in Fundamental and Clinical Immunology – Lugano, Switzerland, 26-30 September 2010.

 

  • Mattei F., Schiavoni G., Spadaro F., Spada M., Fragale A., Sanchez M., Sistigu A., Battistini A., Belardelli F., Gabriele L. “IRF-8 as key mediator of the antitumor immune response in melanoma”. DC2010: Forum on Vaccine Science – 11th International Symposium on Dendritic Cells in Fundamental and Clinical Immunology – Lugano, Switzerland, 26-30 September 2010.

 

  • Palma C., Schiavoni G., Mattei F., Abalsamo L., Piccaro G., Singh M., Cassone A., Gabriele L. “The mycobacterial antigen PstS-1 induces dendritic cell activation and polarizes Ag85B-specific Th-1 and Th17 responses”. DC2010: Forum on Vaccine Science – 11th International Symposium on Dendritic Cells in Fundamental and Clinical Immunology – Lugano, Switzerland, 26-30 September 2010.

 

  • Gabriele L., Schiavoni G., Mattei F., Sanchez M., Sestili P., Butteroni C., Businaro R.,  Afferni C. “The mouse model of Cypress allergy: a new contribution to the evaluation of the health risk of the reforestation”. 29th Congress of the European Academy of Allergy and Clinical Immunology – London, UK, 5-9 June 2010. Allergy. 2010. Vol. 65, Issue Supplement s92. Page 335.

 

  • Gabriele L., Schiavoni G., Mattei F., Sanchez M., Sestili P., Afferni C. “The mouse model of Cypress allergy: a new contribution to the evaluation of the health risk of the reforestation”. International Meeting on health and environment: challenges for the future. Rome, Italy. 9-11 December, 2009.

 

  • Mattei F., Schiavoni G., Spada M., Gabriele L. “Role of IRF-8 in the interface of melanoma tumor cell-immune system interaction”. 2nd European Congress of Immunology – Berlin, Germany, 13-16 September 2009 Eur J Immunol. 2009. Vol. 39. No S1. Page S621. (Oral presentation).

 

  • Schiavoni G., Lorenzi S., Mattei F., Gabriele L. “Type I IFN promote cross-presentation of apoptotic cell-derived antigen by CD8alpha+ DC and stimulate the cross-priming of CD8 T cells”. 2nd European Congress of Immunology – Berlin, Germany, 13-16 September 2009. Eur J Immunol. 2009. Vol. 39. No S1. Page S192.

 

  • Palma C., Schiavoni G., Mattei F., Abalsamo L., Piccaro G., Singh M., Cassone A., Gabriele L. “The mycobacterial antigen PstS-1 induces dendritic cell activation and polarization and modulates Th-1 response evoked by an Ag85B subunit vaccine”. 2nd European Congress of Immunology – Berlin, Germany, 13-16 September 2009. Eur J Immunol. 2009. Vol. 39. No S1. Page S620.

 

  • Bracci L., Schiavoni G., Sistigu A., Lorenzi S., Mattei F., Valentini M., D’Urso M.T., Gabriele L., Proietti E. “Cyclophosphamide treatment spares DC precursors in the bone marrow stimulating their mobilization, peripheral differentiation and tumor-infiltration”. 2nd European Congress of Immunology – Berlin, Germany, 13-16 September 2009. Eur J Immunol. 2009. Vol. 39. No S1. Page 372.

 

  • Schiavoni G., Mattei F., Palma C., Gabriele L. “Differential activity of M. Tuberculosis antigens in the stimulation of neonatal dendritic cell-mediated immune responses”. International Meeting; Needs and Challenges in Translational Medicine: filling the gap between basic research and clinical applications. Rome, Italy. 1-3 October, 2008.

 

  • Bracci L., Schiavoni G., Sistigu A., Lorenzi S., Valentini M., Mattei F., Sestili P., Proietti E. “Involvement of dendritic cell subsets during Cyclophosphamide-induced immune activation: implications for the design of combination therapy protocols against cancer”. International Meeting; Needs and Challenges in Translational Medicine: filling the gap between basic research and clinical applications. Rome, Italy. 1-3 October, 2008.

 

  • Mattei F., Schiavoni G., Borghi P., Venditti M., Canini I., Sestili P., Pietraforte I., Morse III, H.C., Ramoni C., Belardelli F., Gabriele L. “ICSBP/IRF-8 differentially regulates antigen uptake during dendritic cell development and affects antigen presentation to CD4+ T cells”. 9th International Conference on Dendritic Cells, DC2006. Edinburgh, Scotland, 16-20 September, 2006.

 

  • Fragale A., Gabriele L., Borghi P., Sestili P., Stellacci E., Lanciotti A., Venditti M., Schiavoni G., Belardelli F., Battistini A. Interferon regulatory factor-1 is required for full activation and function af dendritic cells. 6th International Cytokine Conference. Vienna, Austria. 27-31 August, 2006.

 

  • Mattei F., Schiavoni G., Borghi P., Sestili P., Canini I., Venditti M., Ramoni C., Belardelli F., Gabriele L. “ICSBP selectively modulates dendritic cell development by affecting their ability to capture and present soluble antigens” 8th International Symposium on Dendritic Cells – Brugge, Belgium, 17-21 October 2004.

 

  • Schiavoni G., Mattei F., Sestili P., Borghi P., Venditti M., Morse H.C., Belardelli F., Gabriele L. “ICSBP is critically involved in the normal development, trafficking and antigen uptake of dendritic cells” 12th International Congress of Immunology - Montreal, Canada, 18-23 July 2004.

 

  • Schiavoni G., Mattei F., Borghi P., Sestili P., Venditti M., Morse III H. C., Belardelli F., Gabriele L. “ICSBP is critically involved in the normal development, trafficking and antigen uptake of dendritic cells” - Istisan Congressi - International Meeting on Cancer Vaccines - Rome, 19-20 April 2004.

 

  • Schiavoni G., Mattei F., Bracci L., Tough D.F., Belardelli F. “Regulation of dendritic cell turnover and lifespan by type I interferons” 7th International Symphosium on Dendritic Cells - Bamberg, Germany, 19-24 September, 2002.

 

  • Schiavoni G., Mattei F., Sestili P., Borghi P., Venditti M., Morse III, H.C., Belardelli F. Gabriele L. “Selective reduction of CD8 alpha(+) dendritic cells and lack of type I IFN-producing cells in ICSBP knock-out mice.” - 7th International Symphosium on Dendritic Cells - Bamberg, Germany, 19-24 September, 2002. (Oral presentation).

 

  • Schiavoni G., Mattei F., Sestili P., Borghi P., Morse III H.C., Belardelli F., Gabriele L. “Impaired differentiation and activity of dendritic cells in knock-out mice for ICSBP.” - International Meeting: Cytokines as natural adjuvants - Perspectives for vaccine development - Rome, 22-24 April 2002.

 

  • Schiavoni G., Mattei F., Belardelli F. “Regulation of lifespan and turnover of dendritic cells by type I and type II interferons in mice” International Meeting: Cytokines as natural adjuvants - Perspectives for vaccine development - Rome, 22-24 April 2002.

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  • Tough D.F., Schiavoni G., Mattei F., Montoya M., D’Agostino G., Gresser I., Borrow P., Belardelli F., Le Bon A. “Regulation of immune responses by type I interferons” International Meeting: Cytokines as natural adjuvants - Perspectives for vaccine development - Rome, 22-24 April 2002.

 

  • Le Bon A., Schiavoni G., D' Agostino G., Gresser I., Belardelli F., Tough D.F. "The adjuvant activity of type I Interferons: a link between natural and adaptive immunity" 11th International Congress of Immunology - Stockholm, Sweden, 22-27 July 2001.

 

  • Montoya M., Schiavoni G., Mattei F., Gresser I, Belardelli F., Borrow, P., Tough D.F. “Type I interferons produced by dendritic cells promote their phenotypic and functional activation” 11th International Congress of Immunology - Stockholm, Sweden, 22-27 July 2001.

 

  • Schiavoni G., Mattei F., Montoya M., Borrow P., Belardelli F., Tough D.F. “Modulation of dendritic cell function by Type I Interferons” - 6th International Symphosium on Dendritic Cells - Port Douglas, Australia, 26 May-1 June, 2000.

 

  • Schiavoni G., Mattei F., Di Pucchio T., Santini S.M., Belardelli F., Proietti E. “Cyclophosphamide induces Type I IFN expression and augments the number of CD44hi lymphocytes in mice: possible implications for strategies of chemoimmunotherapy of cancer”. J Interferon Cytokine Res. 1999, 19(1):S66.

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